SportsLine's model simulated Seattle vs. San Francisco featuring Brock Purdy, Christian McCaffrey and Geno Smith 10000 times.
[See which team to pick here](https://www.sportsline.com/insiders/49ers-vs-seahawks-nfl-week-15-lines-odds-picks-thursday-night-football-predictions-and-best-bets-from-proven-model/#ttag=12132022_agg_cbssports_picks_football_nfl_model_49ersSeahawksTNFmodel). The Seahawks are averaging 26.3 points with Smith serving as a starting quarterback for the first time since 2014 with the [New York Jets](https://www.cbssports.com/nfl/teams/NYJ/new-york-jets/). [Geno Smith](/nfl/players/1700358/geno-smith/) has been a major reason for the improvement. [You can head to SportsLine now to see the model's picks](https://www.sportsline.com/insiders/49ers-vs-seahawks-nfl-week-15-lines-odds-picks-thursday-night-football-predictions-and-best-bets-from-proven-model/#ttag=12132022_agg_cbssports_picks_football_nfl_model_49ersSeahawksTNFmodel). Here are several [NFL odds](https://www.sportsline.com/nfl/odds/) and betting lines for Seahawks vs. Seahawks](https://www.sportsline.com/nfl/game-forecast/NFL_20221215_SF@SEA/) and just locked in its picks and Thursday Night Football predictions. [Visit SportsLine now to see which side of the Seahawks vs. Bosa is tied for the NFL lead in sacks (14.5) and has at least one sack in six of his last seven games. The Seahawks enter Thursday just behind the [Commanders](https://www.cbssports.com/nfl/teams/WAS/washington-commanders/) and [Giants](https://www.cbssports.com/nfl/teams/NYG/new-york-giants/) (both 7-5-1) for the last postseason spot. [NFL](/nfl/) game 10,000 times, is up more than $7,000 for $100 players on top-rated [NFL picks](https://www.sportsline.com/nfl/picks/) since its inception. [San Francisco 49ers](https://www.cbssports.com/nfl/teams/SF/san-francisco-49ers/) can sweep the season series against the [Seattle Seahawks](https://www.cbssports.com/nfl/teams/SEA/seattle-seahawks/) for the first time since 2011 when the two NFC West rivals collide on Thursday Night Football game at Lumen Field. Seahawks odds from Caesars Sportsbook, while the over/under for total points scored is 43.
The Sporting News was tracking all the key moments as San Francisco and Seattle clash on "Thursday Night Football."
ET (5:15 p.m. - Time: 8:15 p.m. The game will kick off at 8:15 p.m. On 4th and 7, the Niners hustle up to the line as the quarter winds down to try and get Seattle to jump offside — and it works. — Purdy is still Pur-fect on the night (sorry). — Purdy finally misses on a short pass to McCaffrey to ruin his perfect night and bring up 3rd and 9. — After a shot to the end zone gets deflected for an incompletion, it brings up 3rd and 8. He plows forward to convert on 3rd and 1 and bring his tally up to 82 total yards on the night. — Purdy makes one of his first mistakes of the night, and it nearly results in a pick. But on 3rd and 4, Geno throws it short of the sticks to Walker and he can't even pick up the first down. — Lockett comes up with a grab on 3rd and 4 to move the Seahawks close to the edge of the red zone. After two McCaffrey carries up the middle, San Francisco faces a 3rd and 2 to try and seal the win — and the division crown.
The TEAM and TEAM meet in Week 9 of the NFL season. We break down what we know before Week 9 inactives arrive at XXXX a.m./p.m. ET on Sunday.
The Seahawks have five players designated as questionable, including S Joey Blount (back), CB Tre Brown (illness), RB DeeJay Dallas (ankle), S Ryan Neal (knee), and DT Al Woods (Achilles). We don’t have the official inactives report yet as it is released an hour and a half before kickoff, but we know which players are definitely not playing. ET on Amazon Prime Video and the 49ers are a 3.5-point favorite at
The 49ers (9-4) are the hottest team in the NFL, with six straight wins heading into tonight's game. Early season questions about the Niners' ability to get ...
Each game is available live and on demand. "So I have to get back to what I was doing early on, which was taking what they give me and allowing us to have a complementary football team where we all play together and not feel like we are just trying to push the envelope or trying to push our limits to see what we can do. It's not a trend the Seahawks can afford to continue as they find themselves just outside of the top 7 in the NFC ahead of tonight's game. We know what we can do, but we have to stay on schedule." The game between the 49ers vs. The 49ers (9-4) are the hottest team in the NFL, with six straight wins heading into tonight's game.
It's almost difficult to believe the 49ers and Seahawks are fighting for NFC West supremacy. Here's how to watch this Thursday's matchup.
- Kickoff: 8:15 p.m. ET (5:15 p.m. Kickoff is set for 8:15 p.m. 1 p.m. The 49ers travel to Lumen Stadium to take on their division rival. Viewers in local markets will be able to watch the game on local network affiliates. 4:25 p.m. 4:05 p.m. 8:15 p.m. That said, there's still a two-game lead in the NFC West, and it belongs to the 49ers and their equally surprising passer, Brock Purdy. Few could have seen Geno Smith's MVP-caliber season coming this year, especially after the open battle in training camp he was in with Drew Lock. Irrelevant has kept the 49ers relevant with wins in Week 13 and 14, helping mitigate the loss of Garoppolo and keeping San Francisco's Super Bowl aspirations alive.
But how long Purdy would be able to play through his oblique injury lingered all night in the mind of San Francisco coach Kyle Shanahan. “We were going to see ...
[Robbie Gould](http://www.espn.com/nfl/player/_/id/9354/robbie-gould) missed a 43-yard field goal and the Seahawks went 67 yards in 1:25. But man, I just hate losing and gotta figure it out,” Smith said. Purdy finished 17 of 26 for 217 yards, joining “Whenever Kyle dials something up that you know you’re gonna get the ball, you try to speak it into existence. “But he just got comfortable and got better as the game went on. That was that,” Purdy said.