Israel Adesanya

Alex Pereira is the only man to ever knock out Israel Adesanya. Can he repeat his kickboxing feat at UFC 281?

[Carla Esparza](https://www.mmafighting.com/fighter/818/carla-esparza) putting her strawweight belt on the line for the first time in her second run as champion, taking on former titleholder [Zhang Weili](https://www.mmafighting.com/fighter/4539/zhang-weili) in the co-main event, as well as a lightweight clash between [Dustin Poirier](https://www.mmafighting.com/fighter/233/dustin-poirier) and [Michael Chandler](https://www.mmafighting.com/fighter/455/michael-chandler). [Sean Strickland](https://www.mmafighting.com/fighter/2072/sean-strickland) in brutal fashion. [Dana White](https://www.mmafighting.com/fighter/2230/dana-white) posted the cold open for [UFC 281](https://www.mmafighting.com/fight-card/1292/ufc-281), narrated by Sons of Anarchy and Hellboy actor Ron Perlman, looking back at their history ahead of a highly anticipated showdown that headlines the card at Madison Square Garden in New York this Saturday.