Rams vs 49ers

If you're looking to watch this divisional game online without cable, The Sporting News has you covered with streaming information below.

SportsLine simulated San Francisco 49ers vs. Los Angeles Rams on Monday Night Football 10000 times and made its best bets.

Here are the [NFL odds](https://www.sportsline.com/nfl/odds/) and betting lines for Rams vs. [Jalen Ramsey](/nfl/players/2071515/jalen-ramsey/) and defensive lineman [Aaron Donald](/nfl/players/1737460/aaron-donald/) leading the defensive unit. [Visit SportsLine right now to find out which side of the 49ers vs. He's first on the team in sacks (4) and tackles for loss (4) with 11 total tackles. [You can head to SportsLine now to see the model's picks](https://www.sportsline.com/insiders/rams-vs-49ers-nfl-week-4-lines-odds-picks-monday-night-football-predictions-and-best-bets-from-proven-model/#ttag=10012022_agg_cbssports_picks_football_nfl_model_rams49ersMNFmodel). Rams](https://www.sportsline.com/nfl/game-forecast/NFL_20221003_LAR@SF/) matchup and just locked in its picks and MNF predictions. The model also says one side of the spread hits well over 50% of the time. [Fred Warner](/nfl/players/2142098/fred-warner/) is a fast playmaker who runs sideline to sideline. [San Francisco 49ers](https://www.cbssports.com/nfl/teams/SF/san-francisco-49ers/) (1-2) hosting the [Los Angeles Rams](https://www.cbssports.com/nfl/teams/LAR/los-angeles-rams/) (2-1). The model enters Week 4 of the 2022 NFL season on an incredible 139-103 run on top-rated [NFL picks](/nfl/picks/experts) that dates back to the 2017 season. San Francisco is favored by two points in the latest Rams vs. 49ers odds from Caesars Sportsbook, and the over/under is 42.5.