Colorectal cancer

2022 - 6 - 8

Post cover — Image courtesy of "CBS News"

Every patient in this experimental drug trial saw their cancer ... (CBS News)

In a small study, patients with rectal cancer got six months of immunotherapy treatment — and doctors say their tumors disappeared.

"The treatment targets a subtype of rectal cancer that has the DNA repair system not working. But they say that seeing complete remission in 100% of patients tested is a very promising early signal. It was administered to each patient every three weeks for six months, and it works by exposing cancer cells so the immune system can identify and destroy them. "The implications for quality of life are substantial, especially in those where standard treatment would impact childbearing potential. These same remarkable results would be seen in 14 patients to date. That's when doctors gave her the good news: She was now cancer-free.

This experimental drug could change the field of cancer research (NPR)

On how the drug works to treat cancer: This drug is one of a class of drugs called immune checkpoint inhibitors. These are immunotherapy medicines that work not ...

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Cancer Drug Makes History as Rectal Tumors Vanish in All Trial ... (Newsweek)

All 12 patients had their rectal tumors disappear after treatment with new experimental drug in small-scale study.

Unfortunately, some cancer cells have large amounts of PD-L1, stopping the body from fighting back. The treatment tested in this paper avoids any of these other health problems. While this has improved the survival rate of colorectal cancer patients, with a three-year disease-free survival rate as high as 77 percent, it's a grueling process and can lead to long-term side effects such as neuropathy, infertility, and bowel and sexual dysfunction.

Small drug trial clears more than a dozen patients of rectal cancer ... (CTV News)

In a small study of more than a dozen patients, researchers found an experimental drug cleared all rectal cancer patients of their tumours.

More than two-thirds of Canadians say rising grocery prices are having a direct impact on their finance-related stress; 56 per cent say the same about soaring gas prices. 9 hr ago Forcing people to work from home, it showed that traditional office models aren’t the only way to get things done. 9 hr ago 9 hr ago 6 hr ago 6 hr ago 9 hr ago 9 hr ago Gill said once more patients surpass longer follow-ups this will also help in furthering research to help patients undergo less stressful treatments. So the immune cells attack with much more force,” she said. “They have preserved normal bowel function, bladder function, sexual function, fertility.

'Astonishing' result in drug trial: First time, cancer vanishes in every ... (The Indian Express)

The new study, presented at the annual meeting of the American Society of Clinical Oncology and published Sunday in the New England Journal of Medicine, ...

📣 The above article is for information purposes only and is not intended to be a substitute for professional medical advice. The inspiration for the rectal cancer study came from a clinical trial Dr Diaz led in 2017 that Merck, the drugmaker, funded. Roth was eligible to enter the clinical trial. Tumors vanished in 10 per cent of the trial’s participants. It was a small trial, just 18 rectal cancer patients, every one of whom took the same drug. The medication was given every three weeks for six months and cost about $11,000 per dose.

A new rectal cancer treatment eliminated all tumors in a small group ... (Popular Science)

There's no definitive cure for cancer, but a small clinical trial may lead the way to a powerful new treatment for rectal tumors. A study published Sunday ...

Further research will need to enroll more patients to paint a complete picture of the treatment’s effects and how long remission lasts. This type of cancer is frequently resistant to chemotherapy and radiation, and treatment often requires surgery to remove almost all of the rectum. The study results were based on a small group of people, leaving a possibility that the outcomes may have been from chance. But the standard treatment for rectal cancer with surgery, radiation, and chemotherapy can be particularly hard on people because of the location of the tumor,” said Andrea Cercek, a medical oncologist at Memorial Sloan Kettering Cancer Center in New York and lead study author in a press release. The idea came from oncologist and study co-author Luis Diaz Jr., who found success using immunotherapy on people with colorectal cancer whose tumors had spread to other body parts. There’s no definitive cure for cancer, but a small clinical trial may lead the way to a powerful new treatment for rectal tumors.

Cancer in all patients vanishes for the first time during US drug trial (India Today)

A small-scale trial of a drug for cancer treatment has shown 100% success in removing the tumours and preventing recurrence in patients.

But no negative reaction was seen in the patients involved in the dostarlimab study. The patients were administered dostarlimab every three weeks for six months. Another surprise in store for the patients was the complete absence of significant post-treatment complications, which are usually associated with other forms of cancer treatment. According to the World Health Organisation, nearly 10 million people died in 2020. The trial, albeit small in scale, has brought hopes that cancer can be removed completely without going through long and painful chemotherapy sessions or surgeries. The world may soon be able to get rid of a dreaded disease that is feared for the sheer number of lives it claims — cancer.